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Quito - Cuenca - Guayaquil - Santa Cruz Island - Isabela Island

10 to 15+ Nights from $1,826*
* This sample price: priced within the past 7 days for arrival on 10/21/2024, departure from Chicago CHI (All Airports)(IL), US. Choose your own departure city and dates.

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This 10 night sample itinerary includes:

  • Hotel for 2 nights in Quito
  • Flight from Quito to Cuenca
  • Hotel for 2 nights in Cuenca
  • Flight from Cuenca to Guayaquil
  • Hotel for 1 night in Guayaquil
  • Flight Guayaquil to Santa Cruz Island
  • Hotel for 2 nights in Santa Cruz Island
  • Transfer + Public speedboat to Isabela Island
  • Hotel for 2 nights in Isabela Island
  • Transfer + Public speedboat to Baltra Airport
  • Flight from Baltra Airport (Santa Cruz Island) to Guayaquil
  • Hotel for 1 night in Guayaquil

Combine the best of Colonial Heritage with amazing nature and wildlife! Start your journey at Quito, the capital city of Ecuador and place of the exactly the Middle of the World. Then take a flight to Cuenca, after Quito, Cuenca is Ecuador’s most important and beautiful colonial city. You will then head to Guayaquil, the main port of the Ecuador and the most populous city in the country. Up next take your flight to Santa Cruz Island, the second largest island of the Galapagos and the most populated urban center in the islands. After enjoying the main island, take the public speedboat to Isabela Island, famous for its geology but also provides an interesting display of fauna and flora. Lastly, take your flight to Guayaquil, to later take your flight home. This is a flexible vacation package. Select your number of nights in each city, desired hotel and activities.

Flexible Itinerary

  • Quito

  • Cuenca

  • Guayaquil

  • Galapagos Islands (Santa Cruz)

  • Galapagos Islands (Isabella)

  • Guayaquil

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Price Guidance

The package rates displayed are your total price per person based on Double Occupancy and your Arrival Date and Number of Nights selected. You can change details after selecting your travel date.

Price history for this itinerary (past 7 days):

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*Sample prices on display include ALL taxes & fuel surcharges... read more

Trip Summary

  • Quito

    The Capital City of Ecuador, Quito is nestled in a long, narrow valley in the Ecuadorian Andes boasting a spectacular natural setting. The fantastic city offers an impressive selection of museums, stunning churches and picturesque plazas with a blend of colonial charm and modern architectural treasures. Explore the crown jewel of the city `Old Town` with its vibrant streets lined with restaurants and bars boasting delicious cuisine and a fantastic nightlife. Visit the Plaza de la Independencia, La Iglesia de la Compania de Jesus, Cathedral of Quito, Museo de la Ciudad, La Ronda, El Panecillo, Teleferiqo, Guayasamin Museum, and much more.

  • Cuenca

    Cuenca`s cobblestone streets, graceful ironwork balconies, flowered plazas, museums and religious art treasures recall the city`s long association with Spain. Cuenca is the third-largest city in Ecuador, marked by shining church domes dating from the 15th and 17th centuries. Several Inca ruins and temples, and museums, provide evidence of Cuenca`s role in Ecuador`s rich and storied cultural heritage. Explore the New Cathedral of Cuenca, Old Cathedral of Cuenca, El Cajas National Park, Museo Pumapungo, Calderon Park, Amaru Zoological Biopark, Santa Ana de los Rios de Cuenca Historic Center, Museo de las Culturas Aborigenes, and so much more!

  • Guayaquil

    Guayaquil is the largest city, the most important port in Ecuador, and the gateway to the Galapagos. The city is carved by rivers and estuaries, and is known as the `Pearl of the Pacific`. It boasts a wonderful blend of history, nature, and tradition throughout its historic neighborhoods, parks, and monuments. Visitors will find great shopping opportunities, magnificent museums, historic monuments and sprawling parks in this exciting city. Visit the Simon Bolivar Malecon, La Rotonda, Parque Seminario, Santa Ana Hillside, Municipal Palace, Metropolitan Cathedral of Guayaquil, Las Penas, La Bahia and much more.

  • Galapagos Islands (Santa Cruz)

    The Island of Santa Cruz is the second largest in the Galapagos archipelago with Puerto Ayora the capital being the busiest center of all the islands. The island boasts many activities and is the gateway to surrounding islands, beaches, dive sites and snorkeling on the beautiful South Pacific Seas. The interior of the island is where the massive National Park lies, brimming with plant life and wildlife. Visit the Puerto Ayora, Tortuga Bay, Garrapatero Beach, Galapagos National Park, Carrion Point, Reserva El Chato, Los Gemelos, Lava Tunnels and much more.

  • Galapagos Islands (Isabella)

    Isabela Island is an impressive location in the Galapagos boasting six volcanoes, 5 of which are active. The largest and most intriguing island in the archipelago forming the shape of a giant seahorse is approximately 1 million years old. The island is covered with unique land formations, wildlife and tuff cones, and amazing fauna and flora. Explore the Puerto Villamil, Los Tuneles, Wall of Tears, Flamingo Lagoon, Sierra Negra, Wolf Volcano and much more.

  • Guayaquil

    Guayaquil is the largest city, the most important port in Ecuador, and the gateway to the Galapagos. The city is carved by rivers and estuaries, and is known as the `Pearl of the Pacific`. It boasts a wonderful blend of history, nature, and tradition throughout its historic neighborhoods, parks, and monuments. Visitors will find great shopping opportunities, magnificent museums, historic monuments and sprawling parks in this exciting city. Visit the Simon Bolivar Malecon, La Rotonda, Parque Seminario, Santa Ana Hillside, Municipal Palace, Metropolitan Cathedral of Guayaquil, Las Penas, La Bahia and much more.

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