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Santorini - Heraklion and Kos - Rhodes

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12 to 18+ Nights from $1,458*
* Sample price: priced within the past 7 days for a 10/10/2025 arrival, departing Los Angeles LAX (CA), US. Choose departure city, cabin and dates.

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This 12 night sample itinerary includes:

  • Flight into Santorini Island and out of Rhodes
  • Hotel for 3 nights in Santorini Island
  • Ferry Santorini Island - Heraklion
  • Hotel for 3 nights in Heraklion
  • Flight from Heraklion to Kos Island
  • Hotel for 3 nights in Kos Island
  • Ferry Kos Island - Rhodes
  • Hotel for 3 nights in Rhodes
  • Ferries/hydrofoils for the Islands do not operate in off seasons (autumn and winter) due to weather conditions

Start your dream Greece vacation with a visit to Santorini Island, featuring stunning sunsets and dramatic views and continue to Heraklion on Crete Island with the Minoan Palace of Knossos, charming villages and beaches before flying to Kos Island, Birthplace of Hippocrates, green and lush with lovely beaches and pretty villages. Then catch the ferry to Rhodes Island, with among the best-preserved Medieval Towns of Europe (with the Street of the Knights, the Palace and Hippocrates Square, strong walls, paved paths and elegant stone mansions) plus beautiful Lindos.

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  • Santorini Island

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  • Heraklion (Crete Island)

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  • Kos Island

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  • Rhodes Island

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Greece

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Trip Summary

  • Santorini Island
    Santorini Island

    Santorini is considered to be the most sought after place for a romantic getaway in Greece since there are not many places in the world where you can enjoy exquisitely clear waters while perched on the rim of a massive active volcano in the middle of the sea! Fira, the picturesque capital of the island, is perched high up on the edge of the Caldera, looking like a marvelous painting. Some of the villages are cosmopolitan, some more peaceful; they are surrounded by vast vineyards; whitewashed cliff-top towns with castles affording amazing views out over the Aegean. Soaking up the villages' distinctive traditional atmosphere is a very unique experience.

    Visit and explore the towns of Fira, Oia, and Imerovigli as well as other charming villages, the beaches, Akrotiri Archaeological Site, the monasteries and churches, the Caldera, and much more!

  • Heraklion (Crete Island)
    Heraklion (Crete Island)

    Founded in 824 AD by Arabic Muslim people, Heraklion is home to the world's only comprehensive collection of Minoan artifacts. It has magnificent fortified walls and several other testimonies to the Venetians' time in power. Heraklion is close to the ruins of the palace of Knossos, which in Minoan times was the biggest center of population on Crete. Home to Crete's largest city, Heraklion, as well as immense ruins scattered throughout the region, this prefecture draws attention from history lovers and young travelers looking for the island's nightlife.

    Visit and explore the Minoan Palaces of Knossos and Phaistos, the archaeological site of Gortyn, Heraklion Archaeological Museum, Cretaquarium, Fortress of Koules, the caves of Matala, lovely beaches, charming villages and so much more.

  • Kos Island
    Kos Island

    Birthplace of Hippocrates, green and lush with lovely beaches, pretty villages, fascinating archaeological sites and a great nightlife, Kos Island sits in the middle of the Dodecanese chain of Greek islands that hug the Turkish coastline between Rhodes in the south and Patmos in the north. The capital is also called Kos and it's both an historical and modern town with many archaeological sites opened in the streets and many resorts along the coasts.

    Visit and explore the Sanctuary of Asclepios (Asclepieion), Roman Odeon of Kos, Casa Romana, Church of St. John the Baptist, the Castle of Antimachia, Castle and Old Town of Pyli, the cave of White Stone, Temple of Hercules, Ancient Agora, Castle of Neratzia, and many charming villages and glorious beaches.

  • Rhodes Island
    Rhodes Island

    Rhodes is the largest and most popular island of the Dodecanese, with 300 days of sunshine per year. Its Old Town is a UNESCO World Heritage Site and is among the best-preserved Medieval Towns of Europe with the Street of the Knights, the Palace and Hippocrates Square, strong walls, paved paths and elegant stone mansions. Rhodes also offers some of the cleanest Aegean beaches and splendid natural spots with rich flora and fauna in the mountains, specifically beautiful are the butterflies - tiger moths. High points offering panoramic views are the acropolis in Lindos and Mount Attavyros.

    Visit and explore The Palace of Grand Masters, Ancient Lindos, The Monastery of Filerimos, Acropolis of Rhodes, The Aquarium, The Archaeological Museum, The Valley of Butterflies, charming villages and beautiful beaches.

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