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Rome and Prague by Air

4.9 out of 5 stars
9 Customer Feedbacks 9 Customer Feedbacks
6 to 9+ Nights from $1,426*
* Sample price: priced within the past 7 days for a 12/26/2025 arrival, departing Chicago CHI (All Airports)(IL), US. Choose departure city, cabin and dates.

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Add Outbound & Return Flights

This 6 night sample itinerary includes:

  • Flight into Rome and out of Prague
  • Hotel for 3 nights in Rome
  • Flight from Rome to Prague
  • Hotel for 3 nights in Prague

See beautiful Italy and Czech Republic through two of their most popular cities. Enjoy Rome (the Eternal City, with its stunning architecture and delicious food) and Prague (known for its Old Town Square; changing hands several times which lead to its fantastic combination of art, architecture and lifestyle). Flight is between these destinations.

What Makes Tripmasters Vacation Packages Different?
Unique, fully custom approach to vacation planning
Choose your preferred flight cabin class
Select up to 14 nights in each city during your stay
Pick from a wide selection of accommodation types (hotels, apartments, B&Bs, Guesthouses, and more)
Add transfers, activities and experiences, and more services to enhance your vacation
Live phone and chat support

Flexible Itinerary

  • Rome

    about
  • Prague

    about
Italy
Czech Republic

Customer Reviews

4.9 out of 5 stars

Trip Summary

  • Rome
    Rome

    Rome is undeniably stunning, from its rich ancient culture, delectable cuisine and coffees to its uniquely European experiences. This city is packed full of sights; with thousands of years of history layered upon itself - you'll find everything from Roman ruins to Renaissance art. It's also home to Vatican City, and sights galore.

    Explore and discover the Roman Colosseum and the Arch of Constantine, discover the Vatican, the smallest independent state in the world; throw a coin in the Trevi Fountain, marvel at the Pantheon, sit on the Spanish Steps, wander the Piazzas, eat the best gelato, climb Palatine Hill, walk the Ancient Appian Way and so much more!

  • Prague
    Prague

    Rows of steeples stacked on onion domes pierce the sky, earning Prague the name 'The City of a Thousand Spires'. Prague has stood the test of time: 1,000 years of art and architecture have collided with power politics and religious conflicts. New shops and restaurants have opened, expanding the city's culinary reach far beyond tradition. The arts and theater are thriving in the 'new' Prague and possess a distinctive Czech flavor. All of this frenetic activity plays well against a stunning backdrop of towering churches and centuries-old bridges and alleyways.

    Explore Prague Castle, Charles Bridge, Old Town Square and the Astronomical Clock, Wenceslas Square, the Jewish Quarter and so much more!

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