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Lisbon and Sao Tome Island by Air

7 to 10+ Nights from $2,319*
* Sample price: priced within the past 7 days for a 9/1/2025 arrival, departing New York City NYC (All Airports) (NY), US. Choose departure city, cabin and dates.

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Add Outbound & Return Flights

This 7 night sample itinerary includes:

  • Flight into and out of Lisbon
  • Hotel for 3 nights in Lisbon
  • Flight from Lisbon to Sao Tome Island
  • Hotel for 3 nights in Sao Tome Island
  • Flight from Sao Tome Island to Lisbon
  • Hotel for 1 night in Lisbon

Visit Portugal and Sao Tome and Principe!. Combine visits to beautiful Lisbon (portugese capital set on seven hills, visually striking, laid back, and friendly with ancient charm) and Sao Tome (the largest island of Sao Tomé and Príncipe, with beautiful beaches and landscapes), connected by an intercity flight.

What Makes Tripmasters Vacation Packages Different?
Unique, fully custom approach to vacation planning
Choose your preferred flight cabin class
Select up to 14 nights in each city during your stay
Pick from a wide selection of accommodation types (hotels, apartments, B&Bs, Guesthouses, and more)
Add transfers, activities and experiences, and more services to enhance your vacation
Live phone and chat support

Flexible Itinerary

  • Lisbon

    about
  • Sao Tome Island

    about
  • Lisbon

    about
Sao Tome and Principe
Portugal

Customer Reviews

Trip Summary

  • Lisbon
    Lisbon

    Lisbon, a dazzling city stretching along the Tagus river, makes an enchanting European capital. Its nucleus, an ancient fortress, is now circled by neighborhoods drenched with medieval charm. Handcrafts - from embroidery to leatherwork - are peddled right on the streets. At night, yellow electric tramcars continue to wind their way up and down the hills to the sound of traditional Fado songs. Ample opportunities exist for seeing popular celebrations, for shopping, and for enjoying the nightlife along the riverbank.

    Visit Alfama, Baixa and Chiado, Se de Lisboa, Sao Roque Church, Mosteiro dos Jeronimos, Torre de Belem, Discoveries Monument, Museu Nacional dos Coches, Parque das Nacos, Elevador de Santa Justa, Tram 28 and so much more!

  • Sao Tome Island
    Sao Tome Island

    The sheer natural beauty of Sao Tome Island is astonishing. Lush tropical rainforests, rugged coastlines, ocean views, hidden coves and beaches, volcanoes, waterfalls and prominent peaks, the list goes on. This is a destination that boasts pristine nature at every turn. Moreover, this beautiful island can be visited all year round, and visitors favourite time of the year is in between February, August or December, as it comes with sunny temperatures, great scuba and snorkelling conditions for all levels, and clear hiking trails in the lush rainforests.

    Popular sites include Saint Nicholas Waterfall, Cao Grande Peak, Lagoa Azul, Praia Jale, Pico de Sao Tome, Praia Micondo, Obo National Park, Forte de Sao Sebastiao and much more.

  • Lisbon
    Lisbon

    Lisbon, a dazzling city stretching along the Tagus river, makes an enchanting European capital. Its nucleus, an ancient fortress, is now circled by neighborhoods drenched with medieval charm. Handcrafts - from embroidery to leatherwork - are peddled right on the streets. At night, yellow electric tramcars continue to wind their way up and down the hills to the sound of traditional Fado songs. Ample opportunities exist for seeing popular celebrations, for shopping, and for enjoying the nightlife along the riverbank.

    Visit Alfama, Baixa and Chiado, Se de Lisboa, Sao Roque Church, Mosteiro dos Jeronimos, Torre de Belem, Discoveries Monument, Museu Nacional dos Coches, Parque das Nacos, Elevador de Santa Justa, Tram 28 and so much more!

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