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Runway to Ride: Santiago - Puerto Natales - El Calafate - Ushuaia - Buenos Aires

10 Nights from $3,407*
* Sample price: priced within the past 7 days for a 9/18/2026 arrival, departing Raleigh RDU (NC), US. Choose departure city, cabin and dates.

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This 10 night sample itinerary price includes:

  • Flight into Santiago and out of Buenos Aires
  • Hotel for 2 nights in Santiago
  • Flight from Santiago to Punta Arenas
  • Transfer from Punta Arenas Airport to Puerto Natales
  • Hotel for 2 nights in Puerto Natales
  • Ground transfer Puerto Natales to El Calafate
  • Hotel for 2 nights in El Calafate
  • Flight from El Calafate to Ushuaia
  • Hotel for 2 nights in Ushuaia
  • Flight from Ushuaia to Buenos Aires
  • Hotel for 2 nights in Buenos Aires

Visit Santiago (a truly cosmopolitan city able to preserve its traditions, located close to vineyards, wineries, ski resorts and beach towns), Puerto Natales (located on the Strait of Magellan, which connects the Atlantic and Pacific oceans, it's often used as base for excursions to the surrounding wilderness and Antarctica), Calafate (known for the imposing and legendary Perito Moreno Glacier), Ushuaia (located on the Tierra del Fuego archipelago, the southernmost tip of South America, nicknamed the “End of the World.”) and Buenos Aires (to stroll in the streets of the Paris of South America and experience one of their Tango Shows). 

What Makes Tripmasters Vacation Packages Different?
Unique, fully custom approach to vacation planning
Choose your preferred flight cabin class
Select up to 14 nights in each city during your stay
Pick from a wide selection of accommodation types (hotels, apartments, B&Bs, Guesthouses, and more)
Add transfers, activities and experiences, and more services to enhance your vacation
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