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The Mighty Mississippi Trail from New Orleans (Self Drive)

9 to 13+ Nights from $1,252*
* This sample price: priced within the past 7 days for check-in on 3/2/2025. Choose your own arrival dates.

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This 9 night sample itinerary includes:

  • Rental Car for 10 days
  • Hotel for 3 nights in New Orleans
  • Hotel for 2 nights in Baton Rouge
  • Hotel for 1 night in Natchez
  • Hotel for 1 night in Vicksburg
  • Hotel for 2 nights in Memphis
  • Driving Time
    New Orleans - Baton Rouge: 1 hr. 21 mins. approx.
    Baton Rouge - Natchez: 1 hr. 38 mins. approx.
    Natchez - Vicksburg: 1 hr. 23 mins. approx.
    Vicksburg - Memphis: 3 hrs. 39 mins. approx

Today you begin your journey following the fantastic Mississippi River through the southern states of Louisiana, Mississippi and Tennessee. Combine New Orleans (a city famous for its music, Creole cuisine, and its annual Mardi Gras Carnival celebration), Baton Rouge, Natchez, Vicksburg and Memphis (one of the most historic and culturally significant cities in the southern United States and home of the blues and rock and roll). The river and these cities were historically incredibly important to trade and livelihood for the earliest Americans. This is a flexible vacation package. Select your number of nights in each city, desired hotel and activities.

Flexible Itinerary

  • New Orleans, LA

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  • Baton Rouge, LA

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  • Natchez, MS

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  • Vicksburg, MS

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  • Memphis, TN

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Trip Summary

  • New Orleans, LA
    New Orleans, LA

    New Orleans is famous worldwide for its distinct music, Creole cuisine, unique dialect, and its annual celebrations and festivals, most notably Mardi Gras. In the French Quarter you will love the French and Spanish Creole architecture and vibrant round-the-clock nightlife along Bourbon Street. Cravings for an unforgettable experience? Hit ``The Big Easy``, where you will experience the world-renowned nightlife, a vibrant live-music scene and spicy, singular cuisine reflecting its history as a melting pot of French, African and American cultures.

    Visit and explore The French Quarter, Jackson Square, Frenchmen Street, Garden District, The National WWII Museum, New Orleans Swamp Tours, Cemetery Tours, The Cabildo, St. Louis Cathedral, and more.

  • Baton Rouge, LA
    Baton Rouge, LA

    The City of Baton Rouge is Louisiana's Capital City and the hub of varied activities. Antebellum landmarks, museums, great local restaurants and hotels are found in Baton Rouge, also home of the Louisiana State University, the LSU System`s flagship university and the largest institution of higher education in the state. Aside from the happening activities and first class cuisine, here you will find historic landmarks including the Old Louisiana State Capitol, the Magnolia Mound Plantation, with its French Creole house, the LSU Rural Life Museum, a complex of refurbished buildings illustrating 18th- and 19th-century life, and the imposing USS Kidd WWII destroyer, moored on the mighty Mississippi.

    Visit the Old Louisiana State Capitol, Magnolia Mound Plantation, LSU Rural Life Museum, USS Kidd Veteran`s Museum, Blue Bayou Water Park, and more.

  • Natchez, MS
    Natchez, MS

    Natchez is a vibrant, and beautiful historic city, where preservation and progress go hand in hand. Set on the Mississippi River, it`s known for antebellum mansions like the unfinished, octagonal Longwood, and the Melrose estate, part of the Natchez National Historical Park. For over 300 years this Jewel of the Mississippi, the oldest city, perched on the highest bluff on the Great River, has been welcoming visitors from all over the world. Natchez is definitely one of the southeastern USA's hidden gems.

    Explore the Natchez National Historical Park, Rosalie Mansion, Longwood, Stanton Hall, Melrose, Natchez Trace Parkway, Grand Village of the Natchez Indians, and more.

  • Vicksburg, MS
    Vicksburg, MS

    Vicksburg is known for being the site of a key Civil War battle. The Siege of Vicksburg is commemorated at the vast Vicksburg National Military Park, which encompasses the Vicksburg National Cemetery and the restored USS Cairo gunboat, and the Old Court House has a museum displaying Civil War artifacts. This city has a major historic significance in American history; To Confederate President Jefferson Davis, Vicksburg was the "nailhead that holds the South's two halves together". President Abraham Lincoln remarked "Vicksburg is the key" to victory, and could be the north's lifeline into the south.

    Explore the Vicksburg National Military Park, Vicksburg National Cemetery, USS Cairo gunboat, Old Court House, Lower Mississippi River Museum, and more.

  • Memphis, TN
    Memphis, TN

    Memphis provides a variety of attractions, restaurants, history, nightlife and other things to do. Memphis is a hotbed of more specialized, often more powerful museums, featuring small yet important collections of art and history. Memphis is also famous for the influential strains of blues, soul, and rock `n` roll that originated there. Memphis is also famous for the influential strains of blues, soul, and rock `n` roll that originated there. With legendary music attractions including Graceland, home of `The King`, many civil rights sites, an award-winning zoo, a world-famous Beale Street and the mighty Mississippi River at the heart of signature Memphis experiences, you`ll find plenty to do on your next vacation.

    Explore The Graceland, the Beale Street, the National Civil Rights Museum, the Stax Museum of American Soul Music, the Sun Studio, the Memphis Zoo, the Memphis Rock `n` Soul Museum, the Mud Island, the Shelby Farms Park, the Memphis Botanic Garden and so much more!

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