Depending on a hotel's primary purpose, its location is a major consideration:

Major Cities: Look for hotels that are located in the city, close to the major points of interest. The walkability of big cities in Africa, like in other parts of the world, can vary widely from city to city. Staying in a centrally located property, close to the main attractions, with nice restaurants in the area, etc, is ideal.

Remember, you are there to visit, so although, the price of the hotel may be slightly higher, you will save tons of money on transportation. Plus the convenience of being able to go back to the hotel easily to drop off items if you are shopping or to get ready for dinner are worth every penny.

Beach Resort or Island Destinations: If you are traveling to a beach resort, a beachfront location or access to the beach will be very important. Do remember, that beachfront locations will most probably be a little more expensive. But as your vacation will be based around the beach and the property, the location and the amenities included will definitely affect the quality of your vacation.

Inland Resorts: A lakefront location or mountain backdrop combined with access to towns or cities will make a difference in pricing.