Bolivia

Runway to Ride: La Paz - Santa Cruz de la Sierra - Sucre - Potosi - Uyuni

7 Nights from $4,257*

* Sample price: priced within the past 7 days for a 5/8/2026 arrival, departing Charlotte CLT (NC), US. Choose departure city, cabin and dates.

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This 7 night sample itinerary price includes:

Flight into La Paz and out of Sucre
Hotel for 2 nights in La Paz
Flight from La Paz to Santa Cruz de la Sierra
Hotel for 1 night in Santa Cruz de la Sierra
Flight from Santa Cruz de la Sierra to Sucre
Hotel for 1 night in Sucre
Transfer from Hotel in Sucre to Hotel in Potosi
Hotel for 1 night in Potosi
Transfer from Hotel in Potosi to Hotel in Uyuni
Hotel for 2 nights in Uyuni
Transfer from Hotel in Uyuni to Airport in Sucre

Discover the culture, food and customs of Bolivia!. Experience La Paz (the highest capital city in the world an important cultural center of Latin America; renowned for its unique markets and colonial buildings), up next fly to Santa Cruz de la Sierra (most economically prosperous city in the country; known for its exciting nightlife) and after that, to Sucre (renowned for being one of South America's most impressive colonial cities). From here with transfers travel to the highland colonial city of Potosi (best known for its underground mining of silver exploited from nearby Cerro Rico) and Uyuni (this city its the gateway to the biggest salt flat in the world: The Uyuni Salt Flat). Finally, a transfer will take you to the Sucre Airport to take your flight back home.

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Bolivia

This country offers breathtaking panoramas from the eternal glaciers of the Andes to the Amazon jungle. A unique legacy of millenary cultures within a clean and safe environment is complemented with the symbiosis of races. Bolivia's smiling people are hospitable and proud of its past. Last but not least, Bolivia has a modern infrastructure and good connections with neighboring countries and beyond. The most outstanding attraction is Lake Titicaca. Comprehensive Andean programs cover Lake Titicaca combined with the archeological destination of Cuzco and Machu Picchu.

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La Paz

La Paz is becoming a must-visit destination on the South American gringo trail, partly due to its convenient location between many of Bolivia's and Peru's greatest sites. But this bustling metropolis at a breathtaking 11,600 feet above sea level has plenty of worthwhile attractions of its own. Warm clothes are a must, almost any time of year, and do take time to get used to the high altitude before doing serious touring. La Paz isn't on every traveler's radar, but it should be. It's an amazing city, set among the Andes Mountains and is the highest capital in the world.

Explore the Valle de la Luna, Basilica of Saint Francis, Ethnography Museum, Museo de la Coca, Museo Nacional de Arte, Valle de las Animas, Catedral Metropolitana Basilica Nuestra Senora and much more.

Santa Cruz de la Sierra

Located in tropical east Bolivia, Santa Cruz de la Sierra seems like a totally different world. At only 1.312 feet above sea level, the mountain scenery and high altitude has changed to humid weather and modern vibes - some may say not the 'authentic' Bolivia. However, this other Bolivia, with its exceptional flora and fauna as well as a variety of landscapes from snowy mountains to the curvy Amazon and never ending green forests is exceptionally beautiful and enjoyable.

Visit the Catedral Metropolitana Basilica Menor de San Lorenzo de Santa Cruz, Lomas de Arena Regional Park, Parque El Arenal, Santa Cruz de la Sierra Botanical Garden and much more!

Sucre

Sucre, set in the southern highlands of Bolivia, is the capital of Bolivia. The whitewashed Casa de la Libertad, where Bolivia's Declaration of Independence was signed, houses galleries related to the city's past as the national capital; and on Plaza 25 de Mayo, you will encounter the Metropolitan Cathedral, and the Museo Universitario Charcas USFXCH, featuring religious artifacts and contemporary art. Its many well-preserved 16th-century religious buildings, such as San Lazaro, illustrate the blending of local architectural traditions with styles imported from Europe. As of December 13, 1991, UNESCO declares Sucre a Cultural Heritage of Humanity.

Visit the Museo Universitario Charcas, Metropolitan Cathedral, Plaza 25 de Mayo, Bolivar Park, Casa de la Libertad, Glorieta Castle, Parque Cretacico de Cal Orck'o, Monasterio de La Recoleta, and so much more!

Potosi

The beautiful Potosi is one of the highest cities in the world at 13,419 feet above the sea level. For centuries, it was the location of the Spanish colonial mint. Potosi lies at the foot of the Cerro de Potosi, sometimes referred to as the Cerro Rico, a gorgeous mountain popularly conceived of as being made of silver ore. It also offers fantastic lunar landscapes, incredible alpine regions, one of the highest lakes on earth and a fascinating, yet unique indigenous culture. The Salar of Uyuni also holds a world record, with an area of 4650 square miles, it is the largest salt lake in the whole world. In addition to this, the Tiwanaku Ruin Site is one of the most important pre-Columbian sites in all of South America, usually referred as the Bolivian Machu Picchu.

Visit the National Mint of Bolivia, Cathedral Basilica of Our Lady of Peace, Templo y Convento de Santa Teresa, Church of Saint Lawrence of Carangas, Cathedral of Saint Francis and much more.

Uyuni

Uyuni lies on the cold, windswept Altiplano, a high intermontane plateau, at 12,024 feet above sea level, just east of the vast Uyuni Salt Flat. The Salar de Uyuni is one of the main tourist destinations in Bolivia as it is visited by approximately 60,000 tourists each year. The best time to visit the Salar de Uyuni is November, the breeding month for the three species of elegant flamingos that live near the many lagoons in the area. The salt flat reflects the clouds, when it is slightly covered with water. Especially between the months of January and March, in the rainy season.

Visit the Train Cemetery, Plaza Principal Aniceto Arce, Senda Andina, Salt Flats, Museo de Trenes, and so much more!

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Runway to Ride: La Paz - Santa Cruz de la Sierra - Sucre - Potosi - Uyuni

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This 7 night sample itinerary price includes:

Bolivia

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Runway to Ride: La Paz - Santa Cruz de la Sierra - Sucre - Potosi - Uyuni