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Santiago - Puerto Natales - El Calafate - Ushuaia - Buenos Aires

10 to 15+ Nights from $2,855*
* Sample price: priced within the past 7 days for a 8/16/2025 arrival, departing Miami MIA (FL), US. Choose departure city, cabin and dates.

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This 10 night sample itinerary includes:

  • Flight into Santiago and out of Buenos Aires
  • Hotel for 2 nights in Santiago
  • Flight from Santiago to Punta Arenas
  • Transfer from Punta Arenas Airport to Puerto Natales
  • Hotel for 2 nights in Puerto Natales
  • Ground transfer Puerto Natales to El Calafate
  • Hotel for 2 nights in El Calafate
  • Flight from El Calafate to Ushuaia
  • Hotel for 2 nights in Ushuaia
  • Flight from Ushuaia to Buenos Aires
  • Hotel for 2 nights in Buenos Aires

Visit Santiago (a truly cosmopolitan city able to preserve its traditions, located close to vineyards, wineries, ski resorts and beach towns), Puerto Natales (from where you will immerse in a fabulous cruise, the Skorpios III, from this cruise you will navigate the Kaweskar Explorers Route during three nights and discover amazing landscapes, glaciers, mountains and multicolored icebergs), Calafate (known for the imposing and legendary Perito Moreno Glacier), Ushuaia (located on the Tierra del Fuego archipelago, the southernmost tip of South America, nicknamed the “End of the World.”) and Buenos Aires (to stroll in the streets of the Paris of South America and experience one of their Tango Shows). 

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Select up to 14 nights in each city during your stay
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Flexible Itinerary

  • Santiago

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  • Puerto Natales

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  • El Calafate (Lago Argentino)

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  • Ushuaia (Tierra del Fuego)

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  • Buenos Aires

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Chile
Argentina

Customer Reviews

Trip Summary

  • Santiago
    Santiago

    Santiago is the gateway to the Chilean Andes and the South Pacific Ocean. Visitors can enjoy world-class skiing and beautiful beaches all in the same day. The sprawling city percolates with activities, including museums, markets and parks spread throughout the many neighborhoods.

    Visit the Plaza de Armas, Metropolitan Cathedral, La Chascona, Maipo Valley, Museum of Memory and Human Rights, La Moneda, Mercado Central, Sky Costanera and much more.

  • Puerto Natales
    Puerto Natales

    Puerto Natales is the port of call for ferries servicing much of the southern coast of Chile, and is itself a stunning location with the sea to one side and on the other - grand views of the Paine Massif, the Southern Ice Field Glaciers and snow-capped peaks of the Riesco Mountain Range in the distance.

    Explore the Torres del Paine, Monumento de la Mano, Municipal Historic Museum, and so much more!

  • El Calafate (Lago Argentino)
    El Calafate (Lago Argentino)

    El Calafate is the gateway to Los Glaciares National Park, which is home to the spectacular sight of the Perito Moreno Glacier and the sprawling Upsala formation. Visitors can see the glaciers up close and personal on tours by boat, trekking or go kayaking on the milky turquoise waters. There are many outdoor activities and adventures to enjoy in the Patagonian Region and the picturesque town offers lakeside views with accommodations, restaurants, and shops.

    Visit the Perito Moreno, Upsala Glacier, La Leona Petrified Forest, Lake Argentino, Viedma Glacier and Lake, Glaciarium Museum, El Centro de Interpretacion Historica and much more.

  • Ushuaia (Tierra del Fuego)
    Ushuaia (Tierra del Fuego)

    The stunning scenery in Ushuaia is simply breathtaking, boasting the sprawling Tierra del Fuego National Park covering thousands of acres of forests, mountains, glaciers and the jaw-dropping scenery of the Beagle Channel. Hiking and Trekking are some of the main draws to the region through the varying terrain, along with canoeing, four-wheel drive tours, skiing and birdwatching. Ushuaia is the gateway to Antarctica, a popular port for cruise ships stopping off for day tours in the area.

    Visit the Tierra del Fuego National Park, Beagle Channel, Sea Wolves Island, The End of the World Train, Lakes Escondido, and much more!

  • Buenos Aires
    Buenos Aires

    Buenos Aires is Argentina's cultural epicenter, known for its music and dance, its cuisine, fine wines, and vibrant night life. Although it has retained much of its Colonial European influence the design and architecture in Bueno Aires reflects influences not only from Spain, but in many cases Paris, Rome and other Euro capitals as well.

    Visit La Boca Neighborhood, Casa Rosada, Plaza de Mayo, Colon Theatre, The Obelisco, Woman's Bridge, De la Republica Park, Recoleta Cemetery, Tigre River Delta, Japanese Gardens and so much more!

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