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The South Great River Road from St. Louis

7 to 10+ Nights from $1,055*
* This sample price: priced within the past 7 days for arrival on 8/2/2024. Choose your own arrival dates.

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This 7 night sample itinerary includes:

  • Rental Car for 8 days
  • Hotel for 3 nights in St. Louis, MO
  • Hotel for 2 nights in Great River Road South, IL
  • Hotel for 2 nights in Memphis, TN
  • Driving Time
    St. Louis, MO - Great River Road South, IL: 42 mins. approx.

The Great River Road is a collection of state and local roads that follow the course of the Mississippi River through ten states. A long the southern portion of this drive the Shawnee National Forest is easily accessible. Start this trip in Missouri visiting St. Louis (a major city in Missouri along the Mississippi River, known for the Gateway Arch, the tallest monument constructed in the United States). After that, drive to Illinois, to reach Great River Road South Area (with its 550-mile route on Illinois' western border offers breathtaking views and majestic landscapes that inspire and soothe the soul) and lastly, in Tennessee, enjoy Memphis (one of the more historic and culturally significant cities, home of blues and rock and roll). This is a flexible vacation package. Select your number of nights in each city, desired hotel and activities.

Flexible Itinerary

  • St Louis, MO

  • Great River Road South, IL

  • Memphis, TN

Customer Reviews

Trip Summary

  • St Louis, MO

    St. Louis is a major city in Missouri along the Mississippi River. Its iconic, 630-ft. Gateway Arch, built in the 1960s, honors the early 19th-century explorations of Lewis and Clark and America's westward expansion in general. Replica paddlewheelers ply the river, offering views of the arch. The Soulard district is home to barbecue restaurants and clubs playing blues music.

    Explore The Gateway Arch, Missouri Botanical Garden, Forest Park, Saint Louis Zoo, Saint Louis Science Center, Cahokia Mounds State Historic Site, Tower Grove Park and much more.

  • Great River Road South, IL

    The Great River Road in Illinois National Scenic Byway clocks in at 550 miles and, around the St. Louis metro area, you will be starting the southern portion of the drive. This segment passes through East St. Louis and Collinsville south to Cairo, with cities like Cape Girardeau on the other side of the river in Missouri.

    Explore the Old Chain of Rocks Bridge, East St. Louis, Collinsville, Cahokia Mounds, Holy Family Log Church, Cape Girardeau, St. Vincent`s Seminary, Fort de Chartres State Historic Site, Pierre Menard Home, Fort Kaskaskia, Shawnee National Forest, Thebes Courthouse, Horseshoe Lake Conservation Area, Cairo, Fort Defiance, and so much more!

  • Memphis, TN

    Memphis provides a variety of attractions, restaurants, history, nightlife and other things to do. Memphis is a hotbed of more specialized, often more powerful museums, featuring small yet important collections of art and history. Memphis is also famous for the influential strains of blues, soul, and rock `n` roll that originated there. Memphis is also famous for the influential strains of blues, soul, and rock `n` roll that originated there. With legendary music attractions including Graceland, home of `The King`, many civil rights sites, an award-winning zoo, a world-famous Beale Street and the mighty Mississippi River at the heart of signature Memphis experiences, you`ll find plenty to do on your next vacation.

    Explore The Graceland, the Beale Street, the National Civil Rights Museum, the Stax Museum of American Soul Music, the Sun Studio, the Memphis Zoo, the Memphis Rock `n` Soul Museum, the Mud Island, the Shelby Farms Park, the Memphis Botanic Garden and so much more!

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