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Great River Road South, IL Vacations Packages


The Great River Road takes adventure-seekers on the open road as it parallels the Mississippi River. The Great River Road in Illinois National Scenic Byway clocks in at 550 miles and is arguably the most gorgeous and picture-perfect segment of the drive. The southern segment of the National Scenic Byway passes south of East St. Louis and Collinsville down to Cairo, with cities like Cape Girardeau on the other side of the river in Missouri.

Best Great River Road South, IL Vacation Packages:

The South Great River Road from St. Louis

7 nights from $1,430*

The Great River Road is a collection of state and local roads that follow the course of the Mississippi River through ten states. The cities along the route were integral to the industry and innovation of the earliest days of the United States. A long the southern portion of this drive the Shawnee National Forest is easily accessible. Start this trip with a visit to Missouri, St. Louis (a major city in Missouri along the Mississippi River, known for the Gateway Arch, the tallest monument constructed in the United States). After that, drive to Illinois, Great River Road South (Its 550-mile route on Illinois' western border offers breathtaking views and majestic landscapes that inspire and soothe the soul) and lastly, Tennessee, Memphis (One of the more historic and culturally significant cities, home of blues and rock and roll). This is a flexible vacation package. Select your number of nights in each city, desired hotel and activities.

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Map of the Great River Road (Southern Illinois)

Great River Road South, IL

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