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Panama City and San Andres Island by Air

7 Nights from $1,988*
* Sample price: priced within the past 7 days for a 7/25/2026 arrival, departing Los Angeles LAX (CA), US. Choose departure city, cabin and dates.

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This 7 night sample itinerary price includes:

  • Flight into and out of Panama City
  • Hotel for 3 nights in Panama City
  • Flight from Panama City to San Andres Island
  • Hotel for 3 nights in San Andres Island
  • Flight from San Andres Island to Panama City
  • Hotel for 1 night in Panama City

Explore exciting streets plus an idyllic island across Panama alongside Colombia! Wander through Panama City, a vibrant regional hub for trading bordering lush rainforests, celebrated for The Panama Canal alongside its charming Casco Viejo. Next, catch a flight toward Colombia to discover San Andres Island, boasting a spectacular Sea of Seven Colors where scuba diving in San Andres is world-renowned. Conclude this fantastic getaway by flying back to Panama City for one final stay before heading home.

Fully Flexible Itinerary: Personalize your hotels, transportation, and length of stay in each city. Easily add curated experiences to complete your journey.

Panama
Colombia

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